[Investigating the diagnostic value of MHC-I expression in polymyositis].

OBJECTIVE

To investigate the diagnostic value of MHC-I expression in PM.

METHODS

Analyzing the results of clinical and pathological findings and the immunohistochemical findings of MHC-I expression of 54 cases.

RESULTS

Among the 16 patients with PM, 63 percent patients showed inflammatory infiltration, 94 percent showed MHC-I expression; Among 19 patients with progressive muscular dystrophy, 9 percent patients showed inflammatory infiltration, 11 percent showed MHC-I expression. The other 19 patients showed no inflammatory infiltration and MHC-I expression.

CONCLUSION

MHC-I expression as a diagnostic index of PM was appropriate, which had ideal sensitivity, specificity and negative likelihood ratio.