Frontiers in medicine · 2025
Adult-onset Still's disease during pregnancy: two case reports and a comprehensive literature review.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Xu Wenchao, Huang Shuang, Li Juanli, Li Ting, Lu Yu, Yang Liu, Zhang Jianyu, Li Xue, Chen Jian
Аннотация
BACKGROUND: Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder marked by recurrent fever, rash, arthritis, and multi-organ involvement. Its occurrence with pregnancy complicates diagnosis and management.
OBJECTIVES: To present the diagnosis and treatment process of two pregnant patients with newly diagnosed AOSD.
CASES: Two cases of AOSD were initially diagnosed during pregnancy. Case one involved a pregnant woman at 16 + 2 weeks of gestation with recurrent fevers, rash, and myalgia. She responded well to treatment with methylprednisolone and cyclosporine and subsequently had a normal vaginal delivery. Case two involved a pregnant woman at 30 + 6 weeks of gestation who presented with systemic joint pain and fever. After being diagnosed with AOSD, she underwent a cesarean section. Treatment included methylprednisolone, cyclosporine, and addition of methotrexate postpartum.
CONCLUSION: Adult-onset Still's disease can be triggered by pregnancy, requiring a multidisciplinary approach for optimal management and fetal outcomes.
OBJECTIVES: To present the diagnosis and treatment process of two pregnant patients with newly diagnosed AOSD.
CASES: Two cases of AOSD were initially diagnosed during pregnancy. Case one involved a pregnant woman at 16 + 2 weeks of gestation with recurrent fevers, rash, and myalgia. She responded well to treatment with methylprednisolone and cyclosporine and subsequently had a normal vaginal delivery. Case two involved a pregnant woman at 30 + 6 weeks of gestation who presented with systemic joint pain and fever. After being diagnosed with AOSD, she underwent a cesarean section. Treatment included methylprednisolone, cyclosporine, and addition of methotrexate postpartum.
CONCLUSION: Adult-onset Still's disease can be triggered by pregnancy, requiring a multidisciplinary approach for optimal management and fetal outcomes.