Simultaneous occurrence of polyarteritis nodosa and leukocytoclastic vasculitis.

We report a patient with cutaneous vasculitis and mononeuritis multiplex. He was found to have both medium size arterial disease, characteristic of polyarteritis nodosa, and small vessel involvement, characteristic of leukocytoclastic vasculitis. This represents a rarely reported combination and serves to emphasize their usual nonoverlapping patterns. The apparent limitation upon the distribution of involved vessels may represent underreporting or signify that different pathophysiologic processes damage vessels of different sizes.