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Open forum infectious diseases · 2025

Two Cases of Mycotic Aneurysms Caused by Brucella suis Infection of Aortic Graft Material.

Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Mize Brandi M, Laskey Emily, Damhorst Gregory L, Kraft Colleen S, Escobar Guillermo A

Аннотация

Brucella suis, a zoonotic pathogen, can affect multiple human organ systems causing various clinical manifestations. While aortoiliac involvement is rare worldwide, we report 2 cases of aortic brucellosis following abdominal aortic aneurysm repairs within a 9-year period at a single US institution in Georgia. One case was an infected aortic endograft, which may be the first reported. B suis aortoiliac infections are rare even in endemic areas, thus highlighting how uncommon these cases are in Georgia. Acknowledging the dismal prognosis with symptomatic aortic graft infections, we wish to share our experience in successfully treating them, including an infected aortic endograft. We recommend obtaining a robust history when evaluating individuals with suspected mycotic aneurysms who frequently handle animals. Education on protective equipment and proper handling of animals is imperative to reduce the risk of aortic graft brucellosis infections. Our institutional experience suggests that graft explantation and doxycycline-rifampin are acceptable treatment options.