Primary Intraosseous Paraganglioma of the Femoral Neck: A Case Report and Review of the Literature.

CASE: An 88-year-old woman presented with worsening right hip pain over 2 years. Radiographs were unremarkable, but magnetic resonance imaging identified a femoral neck lesion. A computed tomography-guided biopsy revealed a zellballen pattern of cells positive for chromogranin and synaptophysin. Further workup, including a metaiodobenzylguanidine scan confirmed focal uptake at the right femoral neck. After multidisciplinary discussion, and shared decision-making with the patient, conservative management was chosen.

CONCLUSION

Primary intraosseous paragangliomas are rare, with this case representing only the second reported in femur and third in the appendicular skeleton. It underscores the importance of a multimodal diagnostic approach, individualized treatment plans, and multidisciplinary collaboration.