Association Between Fibromyalgia and Risk of Developing Sarcopenia According SARC-F: A Cross-Sectional Study.

Background

Fibromyalgia (FM) is a condition characterised by chronic pain, which may or may not be associated with muscular stiffness. Sarcopenia is the progressive loss of muscle mass and strength. The loss of muscle mass is a key factor in the progression of both fibromyalgia and sarcopenia and therefore warrants thorough evaluation. It has been demonstrated that obesity directly influences factors that increase pain perception and disease severity and reduce quality of life. The primary objective of this study was to examine the association between fibromyalgia and the increased risk of developing sarcopenia.

Methods

The sample consisted of 84 patients diagnosed with FM. We assessed sociodemographic characteristics, anthropometric variables (circumferential and ultrasound) pain with a Visual Analogue Scale (VAS) and algometry, risk of developing sarcopenia with SARC-F, quality of sleep, anxiety, and depression using validated questionnaires.

Results

A total of 96.3% of the participants were women. Overall, 56.3% of the sample presented a high risk of sarcopenia according to SARC-F, VAS scores showed significant negative correlations with anxiety (p < 0.01) and with almost all algometric measures (p < 0.05). The Fibromyalgia Impact Questionnaire (FIQ) demonstrated a positive and significant correlation with sleep quality (p < 0.01) and depression (p < 0.01). Furthermore, presence of a high risk of sarcopenia according to SARC-F was significantly associated with FIQ scores (p = 0.002) and depression (p < 0.001).

Conclusions

There is a significant association between the impact of FM and a high risk of developing sarcopenia according to SARC-F. This population exhibits a high degree of pain, which are significantly associated with elevated levels of anxiety and depression.