The Journal of the Association of Physicians of India · 2021
The Pattern of Post-viral Arthritis in COVID Pandemic State: An Experience of Tertiary Care Centre.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Jaladhar Prakruthi, S Chandrashekara, Salanke Manasa, Kori Devaraj
Аннотация
BACKGROUND: Acute onset polyarthritis is a common presentation in rheumatology outpatient consultations, which include both post-infectious arthritis and autoimmune rheumatic diseases (AIRDs). COVID pandemic has added to the list of infectious agents that could result in arthritis.
MATERIALS AND METHODS: The retrospective observational study was conducted at a tertiary care centre. The study included patients who presented with clinical suspicion of post-infectious arthritis between July-September 2019 and 2020. The study was extended for another 2 months to include patients who presented between October-November 2020. The patients were categorized into post-viral arthritis, post-COVID arthritis, chikungunya arthritis and AIRDs. The demographics, comorbidities, clinical presentation, examination findings and laboratory parameters and the response to treatment for each participant were collected and assessed.
RESULTS: In the year 2019 and 2020 (July-Sep), the corresponding number of patients analyzed were 20 and 33. The mean duration of presentation was 1.53 (±3.10) weeks. Chikungunya arthritis was noted in 10% of patients in 2019, while it was 15.15% in 2020. Other post-viral arthritis was identified in 65% and 66.67% of patients in 2019 and 2020 respectively. In the second part of the study, 65.68% of patients were classified as post-viral arthritis, including chikungunya arthritis, post-COVID arthritis and other post-viral arthritis. Around 27% were categorized as AIRDs. Rheumatoid factor negativity and anti-nuclear antibody negativity were found to be significant (P 0.0) in categorizing the patients into post-viral arthritis group, while presence of urinary symptoms (P 0.0) classified the patients into reactive arthritis.
CONCLUSION: The study revealed that the presence of chikungunya arthritis across the two years was comparable. Post-COVID arthritis needs to be considered as a potential differential in post-infectious arthritis. There are no identifiable characteristics (clinical or a simple routine laboratory parameter) that could differentiate the causes of post-infectious arthritis from AIRDs.
MATERIALS AND METHODS: The retrospective observational study was conducted at a tertiary care centre. The study included patients who presented with clinical suspicion of post-infectious arthritis between July-September 2019 and 2020. The study was extended for another 2 months to include patients who presented between October-November 2020. The patients were categorized into post-viral arthritis, post-COVID arthritis, chikungunya arthritis and AIRDs. The demographics, comorbidities, clinical presentation, examination findings and laboratory parameters and the response to treatment for each participant were collected and assessed.
RESULTS: In the year 2019 and 2020 (July-Sep), the corresponding number of patients analyzed were 20 and 33. The mean duration of presentation was 1.53 (±3.10) weeks. Chikungunya arthritis was noted in 10% of patients in 2019, while it was 15.15% in 2020. Other post-viral arthritis was identified in 65% and 66.67% of patients in 2019 and 2020 respectively. In the second part of the study, 65.68% of patients were classified as post-viral arthritis, including chikungunya arthritis, post-COVID arthritis and other post-viral arthritis. Around 27% were categorized as AIRDs. Rheumatoid factor negativity and anti-nuclear antibody negativity were found to be significant (P 0.0) in categorizing the patients into post-viral arthritis group, while presence of urinary symptoms (P 0.0) classified the patients into reactive arthritis.
CONCLUSION: The study revealed that the presence of chikungunya arthritis across the two years was comparable. Post-COVID arthritis needs to be considered as a potential differential in post-infectious arthritis. There are no identifiable characteristics (clinical or a simple routine laboratory parameter) that could differentiate the causes of post-infectious arthritis from AIRDs.