Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi‑center study.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gok Kevser, Nas Kemal, Tekeoglu Ibrahim, Sunar Ismihan, Keskin Yasar, Kilic Erkan, Sargin Betul, Acer Kasman Sevtap, Alkan Hakan, Sahin Nilay, Cengiz Gizem, Cuzdan Nihan, Albayrak Gezer İlknur, Keskin Dilek, Mulkoglu Cevriye, Resorlu Hatice, Bal Ajda, Duruoz Mehmet Tuncay, Kucukakkas Okan, Yurdakul Ozan Volkan, Alkan Melikoglu Meltem, Aydin Yildiray, Ayhan Fikriye Figen, Bodur Hatice, Calis Mustafa, Capkin Erhan, Devrimsel Gul, Ecesoy Hilal, Hizmetli Sami, Kamanli Ayhan, Kutluk Oznur, Sen Nesrin, Sendur Omer Faruk, Tolu Sena, Toprak Murat, Tuncer Tiraje
Аннотация
This article aims to evaluate the possible effect of obesity on quality of life, psychological status, and other clinical variables in Psoriatic arthritis (PsA). PsA patients have been recruited by the Turkish League Against Rheumatism-Network from various centers in Turkey in this cross-sectional study. Patients with a body mass index (BMI) ≥ of 30 kg/m2 were considered obese. Differences among patients with regard to obesity status were assessed with health-related quality of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological status (Hospital Anxiety and Depression Scale [HADS]), and disease activity parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of patients with and without obesity. Obese patients had higher median scores of VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis showed that BMI affects the quality of life, depression, and disease activity. Consequently, obesity has significant associations with higher disease activity, lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should also be taken into account in the management of PsA patients.