[Treatment mechanism of the thermal stimuli of moxibustion on rheumatoid arthritis based on the responses of primary lesion cells to temperature].

This study reviews the pathological behaviors of the primary lesion cells in rheumatoid arthritis, including fibroblasts-like synoviocyte, macrophages, and T cells during the progression of the disease. It analyzes the effects of temperature on phenotypic remodeling and molecular signaling pathways of the relevant cells. After deeply exploring the action mechanism of the thermal stimuli of moxibustion on rheumatoid arthritis, it is found that during moxibustion, the different temperatures of moxibustion may influence the primary lesion cells in rheumatoid arthritis by activating different thermosensitive proteins and thermosensitive pathways, so as to alleviate or cure the disease.