The Laryngoscope · 2006
A paranasal tumor associated with tumor-induced osteomalacia.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Inokuchi Go, Tanimoto Hitoshi, Ishida Haruhiko, Sugimoto Toshitsugu, Yamauchi Mika, Miyauchi Akimitsu, Nibu Ken-Ichi
Аннотация
BACKGROUND: Tumor-induced osteomalacia (TIO) is an extremely rare paraneoplastic syndrome associated with mesenchymal tumors in the craniofacial region.
METHODS: We treated a 24-year-old Japanese woman with paranasal sinus tumor and a low serum phosphate level who presented with nasal obstruction and systemic bone fractures. Serum fibroblast growth factor 23 (FGF-23) was measured before and after surgery.
RESULTS: After surgery, her symptoms were resolved and the serum phosphate and FGF-23 levels became normalized.
CONCLUSION: FGF-23 is thought to be a useful diagnostic marker in patients with craniofacial tumors associated with multiple systemic fractures.
METHODS: We treated a 24-year-old Japanese woman with paranasal sinus tumor and a low serum phosphate level who presented with nasal obstruction and systemic bone fractures. Serum fibroblast growth factor 23 (FGF-23) was measured before and after surgery.
RESULTS: After surgery, her symptoms were resolved and the serum phosphate and FGF-23 levels became normalized.
CONCLUSION: FGF-23 is thought to be a useful diagnostic marker in patients with craniofacial tumors associated with multiple systemic fractures.