Control of bovine leptospirosis: Aspects for consideration in a tropical environment.

Due to the complex and dynamic epidemiology of leptospirosis on livestock, control is still controversial and frustrating. In this context, this paper discusses the main challenges and perspectives for the control of bovine leptospirosis, particularly under tropical conditions. In order to reduce the effects of the disease in cattle, it has been proposed that the control should integrate the trinomial antibiotic therapy (mainly streptomycin); vaccination (whole-cell bacterins); and environmental management. This last element should be carefully considered in tropics. Despite the enormous economic impact of the disease, mainly on its chronic and silent reproductive presentation, research on control programs is not proportional. Conversely, the number of studies regarding the new vaccine strategies, such as recombinant antigens has been increasing and should be encouraged.