Медицинская библиотека · ArXiv · 2024

The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods.

Yaniv Ziv, Anidi Ifeanyichukwu U, Arakkal Leanne, Arroyo-Mejías Armando J, Beuschel Rebecca T, Börner Katy, Chu Colin J, Clark Beatrice, Clatworthy Menna R, Colautti Jake, Coscia Fabian, Croteau Joshua, Denha Saven, Dever Rose, Dutra Walderez O, Fritzsche Sonja, Fullam Spencer, Gerner Michael Y, Gola Anita, Gollob Kenneth J, Hernandez Jonathan M, Hor Jyh Liang, Ichise Hiroshi, Jing Zhixin, Jonigk Danny, Kandov Evelyn, Kastenmüller Wolfgang, Koenig Joshua F E, Kothurkar Aanandita, Kortekaas Rosa K, Kreins Alexandra Y, Lamborn Ian T, Lin Yuri, Morais Katia Luciano Pereira, Lunich Aleksandra, Luz Jean C S, MacDonald Ryan B, Makranz Chen, Maltez Vivien I, McDonough John E, Moriarty Ryan V, Ocampo-Godinez Juan M, Olyntho Vitoria M, Oxenius Annette, Padhan Kartika, Remmert Kirsten, Richoz Nathan, Schrom Edward C, Shang Wanjing, Shi Lihong, Shih Rochelle M, Speranza Emily, Stierli Salome, Teichmann Sarah A, Veres Tibor Z, Vierhout Megan, Wachter Brianna T, Williams Margaret, Zangger Nathan, Germain Ronald N, Radtke Andrea J

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Аннотация

The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D and 3D immunofluorescence imaging methods. The design of the Knowledge-Base is modeled after efforts in the open-source software community and includes three facets: a development platform (GitHub), static website, and service for data archiving. The Knowledge-Base facilitates the practice of open science throughout the research life cycle by providing validation data for recommended and non-recommended reagents, e.g., primary and secondary antibodies. In addition to reporting negative data, the Knowledge-Base empowers method adoption and evolution by providing a venue for sharing protocols, videos, datasets, software, and publications. A dedicated discussion forum fosters a sense of community among researchers while addressing questions not covered in published manuscripts. Together, scientists from around the world are advancing scientific discovery at a faster pace, reducing wasted time and effort, and instilling greater confidence in the resulting data.

Для цитирования: Yaniv Ziv, Anidi Ifeanyichukwu U, Arakkal Leanne, Arroyo-Mejías Armando J, Beuschel Rebecca T, Börner Katy, Chu Colin J, Clark Beatrice, Clatworthy Menna R, Colautti Jake, Coscia Fabian, Croteau Joshua, Denha Saven, Dever Rose, Dutra Walderez O, Fritzsche Sonja, Fullam Spencer, Gerner Michael Y, Gola Anita, Gollob Kenneth J, Hernandez Jonathan M, Hor Jyh Liang, Ichise Hiroshi, Jing Zhixin, Jonigk Danny, Kandov Evelyn, Kastenmüller Wolfgang, Koenig Joshua F E, Kothurkar Aanandita, Kortekaas Rosa K, Kreins Alexandra Y, Lamborn Ian T, Lin Yuri, Morais Katia Luciano Pereira, Lunich Aleksandra, Luz Jean C S, MacDonald Ryan B, Makranz Chen, Maltez Vivien I, McDonough John E, Moriarty Ryan V, Ocampo-Godinez Juan M, Olyntho Vitoria M, Oxenius Annette, Padhan Kartika, Remmert Kirsten, Richoz Nathan, Schrom Edward C, Shang Wanjing, Shi Lihong, Shih Rochelle M, Speranza Emily, Stierli Salome, Teichmann Sarah A, Veres Tibor Z, Vierhout Megan, Wachter Brianna T, Williams Margaret, Zangger Nathan, Germain Ronald N, Radtke Andrea J. The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods.. ArXiv. 2024.

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