Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society · 2008
[A case of relapsing polychondritis monitored by repeated measurements of flow-volume curve].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Niju Takashi, Tsuruta Naotoshi, Kuhara Hanako, Saito Yoshiyuki, Hara Hideki
Аннотация
A 57-year-old man was admitted to our hospital with hoarseness, productive cough, and dyspnea. Chest CT revealed a thickening of the tracheal wall, and the flow-volume curve showed a constrictive upper airway flow pattern. Bronchoscopy revealed disappearance of cartilaginous rings and tracheal stenosis. Biopsy of the cricoid cartilage showed findings compatible with relapsing polychondritis and a diagnosis of relapsing polychondritis was made in accordance with Damiani's criteria. The flow-volume curve and symptoms were immediately improved by methylprednisolone pulse therapy, but on reduction of oral prednisorone, recurrence was identified by flow-volume curve and bronchoscopy. Administration of dapson and cyclophosphamide in addition to oral prednisolone after intravenous methylprednisolone and flow-volume curve resulted in improvement. In this case, monitoring of flow-volume curve was useful for the evaluation of airway complication in relapsing polychondritis.