Recent Advancements in Non-surgical Approaches for the Management of Delayed Union and Nonunion in Long Bone Fractures of the Extremities: A Review.

Delayed union and nonunion of long bone fractures are common clinical complications, especially among patients suffering from chronic diseases like osteoporosis and diabetes. Although traditional surgical procedures are commonly applied, they are characterized by numerous problems, such as the need for secondary surgical procedures and the increased risk of complications. On the other hand, non-surgical therapy presents an attractive option since it can avoid the hazards of surgery, prevent complications, and help lower medical expenses. This practice has been gaining interest in recent times. This article will summarize the most recent developments in the non-surgical treatment field for delayed union and nonunion of long bone fractures, which will help improve clinical practice and the discipline of regenerative medicine.