Multifunctional SiO2&PB particles composite coating on a titanium surface enhances the osseointegration of dental implants in diabetes.

Titanium (Ti) implants often fail to perform optimally because of biological inertness and limited antimicrobial activity, especially in patients with systemic conditions like diabetes or osteoporosis. In this study, a porous oxide layer doped with silica (SiO2) particles was formed on Ti via micro-arc oxidation (MAO), and Prussian blue (PB) particles were immobilized onto the surface using polydopamine (PDA) adsorption to create a SiO2&PB composite coating. The coating features micro/nanoscale roughness, strong hydrophilicity, good wear and corrosion resistance, and a near-infrared (NIR) photothermal effect; in vitro it demonstrated antibacterial effects, reactive oxygen species (ROS) scavenging, and promoted osteogenic differentiation. In a diabetic rat extraction-socket model, the coating enhanced early osseointegration, indicating a promising strategy to reduce implant failure in patients with systemic diseases and potential for clinical translation.