Ocular immunology and inflammation · 2013
An exceptional case of full-thickness macular hole closure in a patient with Behçet disease.
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Uçar Didar, Atalay Eray, Özyazgan Yilmaz, Özkök Ahmet, Yıldırım Yeliz
Аннотация
PURPOSE: To present a case of a full-thickness macular hole closure in a patient with Behcet uveitis.
DESIGN: A 23-year-old-male patient with Behcet Disease had clinically inactive uveitis with topical steroids, oral azathiopurine and cyclosporine until he developed a retinal infiltrate in the left eye which evolved into a full-thickness macular hole during the follow-up.
METHODS: Strict control of inflammation and subsequent vitrectomy was planned. Meanwhile another attack of panuveitis developed in the left eye and subcutaneous Interferon alfa-2b interferon treatment was initiated.
RESULTS: After 2 months, the patient was clinically inactive with complete closure of the macular hole.
CONCLUSIONS: Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy.
DESIGN: A 23-year-old-male patient with Behcet Disease had clinically inactive uveitis with topical steroids, oral azathiopurine and cyclosporine until he developed a retinal infiltrate in the left eye which evolved into a full-thickness macular hole during the follow-up.
METHODS: Strict control of inflammation and subsequent vitrectomy was planned. Meanwhile another attack of panuveitis developed in the left eye and subcutaneous Interferon alfa-2b interferon treatment was initiated.
RESULTS: After 2 months, the patient was clinically inactive with complete closure of the macular hole.
CONCLUSIONS: Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy.
Предметные рубрики MeSH
Administration, OralAdministration, TopicalAzathioprineBehcet SyndromeCyclosporineDrug Therapy, CombinationFluorescein AngiographyGlucocorticoidsHumansImmunosuppressive AgentsInterferon alpha-2Interferon-alphaMalePanuveitisRecombinant ProteinsRemission, SpontaneousRetinal PerforationsTomography, Optical CoherenceVisual AcuityYoung Adult