Ocular immunology and inflammation · 2013
Successful treatment with infliximab for Behçet disease during pregnancy.
Клинический случайПисьмо в редакциюНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Takayama Kei, Ishikawa Sho, Enoki Toshio, Kojima Teruo, Takeuchi Masaru
Аннотация
PURPOSE: To report a case of successful treatment with infliximab for Behçet disease (BD) during pregnancy.
DESIGN: A case report.
METHODS: A 30-year-old woman was diagnosed with BD at 12 weeks of pregnancy. Additional symptoms occurred, and infliximab at a dose of 5 mg/kg body weight was initiated at 18 weeks and repeated.
RESULTS: All symptoms improved, and a 3950-g infant was delivered uneventfully without any abnormality at 39 weeks. A few weeks after delivery, uveitis and systemic symptoms relapsed. Infliximab was reinitiated and all symptoms were resolved.
CONCLUSIONS: Infliximab may be safe and effective for BD during pregnancy.
DESIGN: A case report.
METHODS: A 30-year-old woman was diagnosed with BD at 12 weeks of pregnancy. Additional symptoms occurred, and infliximab at a dose of 5 mg/kg body weight was initiated at 18 weeks and repeated.
RESULTS: All symptoms improved, and a 3950-g infant was delivered uneventfully without any abnormality at 39 weeks. A few weeks after delivery, uveitis and systemic symptoms relapsed. Infliximab was reinitiated and all symptoms were resolved.
CONCLUSIONS: Infliximab may be safe and effective for BD during pregnancy.