Медицинская библиотека · Ocular immunology and inflammation · 2013

Successful treatment with infliximab for Behçet disease during pregnancy.

Takayama Kei, Ishikawa Sho, Enoki Toshio, Kojima Teruo, Takeuchi Masaru

Клинический случайПисьмо в редакциюПеревод в очереди

Аннотация

PURPOSE: To report a case of successful treatment with infliximab for Behçet disease (BD) during pregnancy.

DESIGN

A case report.

METHODS

A 30-year-old woman was diagnosed with BD at 12 weeks of pregnancy. Additional symptoms occurred, and infliximab at a dose of 5 mg/kg body weight was initiated at 18 weeks and repeated.

RESULTS

All symptoms improved, and a 3950-g infant was delivered uneventfully without any abnormality at 39 weeks. A few weeks after delivery, uveitis and systemic symptoms relapsed. Infliximab was reinitiated and all symptoms were resolved.

CONCLUSIONS

Infliximab may be safe and effective for BD during pregnancy.

Для цитирования: Takayama Kei, Ishikawa Sho, Enoki Toshio, Kojima Teruo, Takeuchi Masaru. Successful treatment with infliximab for Behçet disease during pregnancy.. Ocular immunology and inflammation. 2013. DOI: 10.3109/09273948.2013.781655.

Предметные рубрики MeSH

Adult Anti-Inflammatory Agents, Non-Steroidal Antibodies, Monoclonal Behcet Syndrome Dose-Response Relationship, Drug Female Fluorescein Angiography Follow-Up Studies Fundus Oculi Humans Infant, Newborn Infliximab Pregnancy Pregnancy Complications Tumor Necrosis Factor-alpha

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