Fibrosarcoma in a patient with scleroderma.

Malignancies have been described in association with various connective tissue disorders. While such associations may be relatively common in some disorders, such as polymyositis, the relationship between scleroderma and malignancy is more controversial. A case of fibrosarcoma of the tibia in a patient with scleroderma is presented, with correlation of conventional radiography, computed tomography, and histopathology.