A neoteric approach to regeneration of intrabony defects using curcumin gel versus bioactive glass as bone replacement material among South Indian population: A randomized controlled trial.

BACKGROUND AND

OBJECTIVES

The trend of using herbal bone replacement material for the regeneration of periodontal intrabony defects is still underexplored in clinical periodontal practice. As there remains a paucity in scientific information regarding this, the present study was carried out to evaluate and compare clinically and radiographically the effectiveness of curcumin gel and bioactive glass as a BRM in treating intrabony defects among the South Indian population.

MATERIALS AND

METHODS

A total of 60 intrabony defects were randomly divided into Group 1 (30 defects treated with curcumin gel) and Group 2 (30 defects treated with bioactive glass). All clinical and radiographic parameters were recorded at baseline, 3 months, 6 months, and 9 months.

RESULTS

All the clinical parameters showed statistically significant intragroup and intergroup improvement at the end of 9 months. There was a statistically significant volumetric bone fill of defect sites, which was 13.64 (61.19%) and 11.51 (49.36%) in Groups 1 and 2, respectively, at the end of 9 months.

CONCLUSION

The present study indicates that curcumin gel has a great potential for bone regeneration in periodontal intrabony defects, along with minimum/no postsurgical side effects due to its herbal nature. Thus, it may serve as a natural alternative to synthetic BRMs.