Diagnostic value of magnetic resonance image compilation (MAGiC) in cervical disc degeneration: a quantitative assessment of multiple parametric markers.

BackgroundCervical disc degeneration represents a significant healthcare challenge that necessitates precise diagnostic methodologies for optimal clinical management. Although conventional magnetic resonance imaging (MRI) remains the gold standard for disc assessment, the emergence of quantitative imaging techniques presents an opportunity to enhance diagnostic accuracy and facilitate objective evaluation of degenerative changes.PurposeTo investigate the feasibility and clinical value of the magnetic resonance image compilation (MAGiC) technique in evaluating cervical intervertebral disc degeneration.Material and MethodsA total of 200 patients (1000 cervical discs) underwent both conventional MRI and MAGiC scanning. Two experienced physicians performed Miyazaki grading on T2-weighted images. Quantitative measurements were taken from the anterior annulus fibrosus (AAF), posterior annulus fibrosus (PAF), and nucleus pulposus (NP) in MAGiC sequences.ResultsHigh consistency was observed in the region of interest (ROI) and Miyazaki grading (ICC > 0.8). T2 and R2 showed significant correlation with age and Miyazaki stage (P <0.001). Significant differences were found between classifications, except for quantitative parameters between grades Ⅰ and Ⅱ of the AAF and PAF regions, and T1 values between grades and PAF regions. NP parameters showed a statistical significance between adjacent Miyazaki grades. MAGiC parameters of NP demonstrated highest diagnostic efficiency for cervical disc degeneration.ConclusionMAGiC technique effectively quantifies cervical degenerative changes, with T2 and R2 values of NP showing highest effectiveness. This method provides accurate diagnostic information and may have clinical potential pending validation.