Pakistan journal of medical sciences · 2025
Evaluation of Eosinophil-to-Lymphocyte Ratio and Eosinophil Count as Predictive Markers in Fibromyalgia Syndrome.
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Raikan Buyukavci, Ilhan Kaya Caglar, Ramazan Yilmaz
Аннотация
OBJECTIVE: This study aimed to investigate the predictive role of eosinophil-to-lymphocyte ratio (ELR), and eosinophil count (EC) in patients with Fibromyalgia syndrome (FMS) and to compare with healthy controls.
METHOD: This retrospective observational study was conducted from January 1st to December 31st, 2024 in Konya Beyhekim Training and Research Hospital. 109 FMS (101 female/8 male) patients who met the 2016 American College of Rheumatology (ACR) classification criteria and 85 (75 female/10 male) healthy controls were included in the study. Demographic characteristics, neutrophil, lymphocyte, and eosinophil counts (EC) levels were recorded. ELR, neutrophil-lymphocyte ratio (NLR) calculated.
RESULTS: In patients with FMS, the blood ELR, NLR, and EC were significantly higher compared to the control group (p<0.05). In the roc curve analysis, blood NLR had 62.4% sensitivity and 50% specificity; blood ELR and EC ≥had 60.6% sensitivity but < 40 % specificity in predicting fibromyalgia.
CONCLUSION: The results of this study showed that ELR and EC are promising inflammatory markers in the diagnosis of fibromyalgia and should be evaluated in a larger population along with other hemogram parameters.
METHOD: This retrospective observational study was conducted from January 1st to December 31st, 2024 in Konya Beyhekim Training and Research Hospital. 109 FMS (101 female/8 male) patients who met the 2016 American College of Rheumatology (ACR) classification criteria and 85 (75 female/10 male) healthy controls were included in the study. Demographic characteristics, neutrophil, lymphocyte, and eosinophil counts (EC) levels were recorded. ELR, neutrophil-lymphocyte ratio (NLR) calculated.
RESULTS: In patients with FMS, the blood ELR, NLR, and EC were significantly higher compared to the control group (p<0.05). In the roc curve analysis, blood NLR had 62.4% sensitivity and 50% specificity; blood ELR and EC ≥had 60.6% sensitivity but < 40 % specificity in predicting fibromyalgia.
CONCLUSION: The results of this study showed that ELR and EC are promising inflammatory markers in the diagnosis of fibromyalgia and should be evaluated in a larger population along with other hemogram parameters.