Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2006
Prognostic factors associated with severe leptospirosis.
Редакционная статьяНазвание и аннотация: Перевод в очереди
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Doudier B, Garcia S, Quennee V, Jarno P, Brouqui P
Аннотация
Leptospirosis is an anthropozoonosis caused by Leptospira interrogans. It occurs worldwide and is endemic in French Polynesia. Leptospirosis is associated with a large variety of clinical symptoms. Most infections caused by leptospires are either sub-clinical or of very mild severity, but 5-10% of infections result in multiple organ damage, including kidney, liver and lung lesions. Among 71 patients hospitalised in Papeete for severe leptospirosis during a period of 2 years, the main risk-factors for a severe outcome were hypotension, oliguria and an abnormal chest auscultation at the first physical examination. Survival depends on rapid diagnosis and early appropriate management. Well-defined criteria may help physicians to improve the timely treatment of high-risk patients.