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DOI 10.1093/omcr/omag005

Медицинская библиотека · Oxford medical case reports · 2026

Post-dengue transverse myelitis: a challenging case of neurological and therapeutic evidence.

Pires Bianca Frigo, de Souza Caroline Goulart Nunes, de Campos Eduardo Coviello Mendes, Rajab Talles, de Albuquerque Mariana Ferreira, do Carmo João Victor Padovani, de Paula Fernanda Ferraioli, Peleckis Luiz Guilherme, Foroni Bruno Tolentino, Navarrete Clara Luisa Negraes, de Souza Fernanda Goulart Nunes, de Moura Vardasca Gustavo Henrique, Croccia Natalia Seno, Campos Raiza Marques Vieira, Okaji Ruy Yoshiaki

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Аннотация

INTRODUCTION

Dengue is an arbovirus with significant global prevalence that can lead to severe neurological complications, such as longitudinally extensive transverse myelitis (LEMT).

CASE REPORT: We describe a 36-year-old man who developed sudden paraparesis and urinary retention approximately ten days after dengue infection. MRI revealed longitudinal hyperintense lesions in the cervical and thoracic spinal cord. Cerebrospinal fluid analysis revealed an inflammatory pattern and dengue serology was positive. The patient was treated with intravenous methylprednisolone and rehabilitation, leading to gradual neurological improvement and functional recovery.

DISCUSSION: Post-dengue transverse myelitis may result from parainfectious or post-infectious autoimmune mechanisms, often accompanied by demyelination and spinal cord inflammation. The low rate of DENV IgM in the CSF reinforces the immune-mediated hypothesis. Prognosis varies depending on the early intervention and the extent of spinal injury. Underreporting remains a challenge, and future studies should explore biomarkers and develop standardized management protocols.

Для цитирования: Pires Bianca Frigo, de Souza Caroline Goulart Nunes, de Campos Eduardo Coviello Mendes, Rajab Talles, de Albuquerque Mariana Ferreira, do Carmo João Victor Padovani, de Paula Fernanda Ferraioli, Peleckis Luiz Guilherme, Foroni Bruno Tolentino, Navarrete Clara Luisa Negraes, de Souza Fernanda Goulart Nunes, de Moura Vardasca Gustavo Henrique, Croccia Natalia Seno, Campos Raiza Marques Vieira, Okaji Ruy Yoshiaki. Post-dengue transverse myelitis: a challenging case of neurological and therapeutic evidence.. Oxford medical case reports. 2026. DOI: 10.1093/omcr/omag005.
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