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DOI 10.3390/jcm12175565

Медицинская библиотека · Journal of clinical medicine · 2023

Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.

Passias Peter G, Williamson Tyler K, Mir Jamshaid M, Smith Justin S, Lafage Virginie, Lafage Renaud, Line Breton, Daniels Alan H, Gum Jeffrey L, Schoenfeld Andrew J, Hamilton David Kojo, Soroceanu Alex, Scheer Justin K, Eastlack Robert, Mundis Gregory M, Diebo Bassel, Kebaish Khaled M, Hostin Richard A, Gupta Munish C, Kim Han Jo, Klineberg Eric O, Ames Christopher P, Hart Robert A, Burton Douglas C, Schwab Frank J, Shaffrey Christopher I, Bess Shay, On Behalf Of The International Spine Study Group

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Аннотация

BACKGROUND

While reimbursement is centered on 90-day outcomes, many patients may still achieve optimal, long-term outcomes following adult spinal deformity (ASD) surgery despite transient short-term complications.

OBJECTIVE

Compare long-term clinical success and cost-utility between patients achieving optimal realignment and suboptimally aligned peers.

STUDY DESIGN/

SETTING

Retrospective cohort study of a prospectively collected multicenter database.

METHODS

ASD patients with two-year (2Y) data included. Groups were propensity score matched (PSM) for age, frailty, body mass index (BMI), Charlson Comorbidity Index (CCI), and baseline deformity. Optimal radiographic criteria are defined as meeting low deformity in all three (Scoliosis Research Society) SRS-Schwab parameters or being proportioned in Global Alignment and Proportionality (GAP). Cost-per-QALY was calculated for each time point. Multivariable logistic regression analysis and ANCOVA (analysis of covariance) adjusting for baseline disability and deformity (pelvic incidence (PI), pelvic incidence minus lumbar lordosis (PI-LL)) were used to determine the significance of surgical details, complications, clinical outcomes, and cost-utility.

RESULTS

A total of 930 patients were considered. Following PSM, 253 "optimal" (O) and 253 "not optimal" (NO) patients were assessed. The O group underwent more invasive procedures and had more levels fused. Analysis of complications by two years showed that the O group suffered less overall major (38% vs. 52%, p = 0.021) and major mechanical complications (12% vs. 22%, p = 0.002), and less reoperations (23% vs. 33%, p = 0.008). Adjusted analysis revealed O patients more often met MCID (minimal clinically important difference) in SF-36 PCS, SRS-22 Pain, and Appearance. Cost-utility-adjusted analysis determined that the O group generated better cost-utility by one year and maintained lower overall cost and costs per QALY (both p < 0.001) at two years.

CONCLUSIONS

Fewer late complications (mechanical and reoperations) are seen in optimally aligned patients, leading to better long-term cost-utility overall. Therefore, the current focus on avoiding short-term complications may be counterproductive, as achieving optimal surgical correction is critical for long-term success.

Для цитирования: Passias Peter G, Williamson Tyler K, Mir Jamshaid M, Smith Justin S, Lafage Virginie, Lafage Renaud, Line Breton, Daniels Alan H, Gum Jeffrey L, Schoenfeld Andrew J, Hamilton David Kojo, Soroceanu Alex, Scheer Justin K, Eastlack Robert, Mundis Gregory M, Diebo Bassel, Kebaish Khaled M, Hostin Richard A, Gupta Munish C, Kim Han Jo, Klineberg Eric O, Ames Christopher P, Hart Robert A, Burton Douglas C, Schwab Frank J, Shaffrey Christopher I, Bess Shay, On Behalf Of The International Spine Study Group. Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.. Journal of clinical medicine. 2023. DOI: 10.3390/jcm12175565.
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