Консенсусные рекомендации по управлению множественным склерозом в Австралии и Новой Зеландии: часть 1.
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История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shipley Jessica, Beharry James, Yeh Wei, Seery Nabil, Foong Yi Chao, Ayton Darshini, Siriratnam Pakeeran, Tan Tracie, Beadnall Heidi, Barton Joshua, Bridge Francesca, Wesselingh Robb, Taylor Lisa, Rath Louise, Haartsen Jodi, Gadi Mohammad, Nesbitt Cassie, Zhong Michael, Cushing Victoria, McKay Fiona, Morahan Julia, Trewin Benjamin Peter, Roos Izanne, Marriott Mark, Nguyen Ai-Lan, Downey Emma, Crosby Joanne, Bosco Julian, Taylor Jennifer, Giles Lauren, John Nevin, Butler Ernest, van der Walt Anneke, Butzkueven Helmut, Blum Stefan, Simpson Marion, Slee Mark, Ramanathan Sudarshini, Hardy Todd, Macdonell Richard A L, Buzzard Katherine, Mason Deborah F, Lechner-Scott Jeannette, Kilpatrick Trevor J, Kalincik Tomas, Taylor Bruce V, Broadley Simon A, Reddel Stephen, Johnson Douglas, Monif Mastura, MS Interest Group, Australian and New Zealand Association of Neurologists
Аннотация
Оригинал публикации
Consensus recommendations on multiple sclerosis management in Australia and New Zealand: part 1.
INTRODUCTION: Multiple sclerosis (MS) is a chronic inflammatory demyelinating and degenerative disease of the central nervous system. There were 33 335 people with MS in Australia in 2021 and 2917 in New Zealand in 2006 and the prevalence and incidence are increasing with time. Although new treatments have substantially improved outcomes in recent decades, the treatment landscape has become increasingly complex due to the expanding number of disease-modifying therapies (DMTs) and associated safety considerations.
MAIN RECOMMENDATIONS: A total of 80 consensus recommendations were developed on the current best-practice management of MS in Australia and New Zealand. Part 1 of these guidelines outlines the consensus recommendations covering domains including DMT counselling and selection, pre-DMT assessments, monitoring disease activity on DMT, switching DMT, and discontinuing DMT. The remaining recommendations are outlined in Part 2, encompassing risk mitigation strategies during treatment with DMT, managing DMT in special situations (including pregnancy, postpartum, breastfeeding, active infection including COVID-19, and malignancy), general lifestyle measures, acute MS relapses, and symptomatic treatments for MS.
CHANGES IN MANAGEMENT AS A RESULT OF THE GUIDELINES: This two-part position statement provides a practical resource for clinicians on current best-practice consensus recommendations for managing adults (≥ 18 years old) with MS in the Australian and New Zealand health care settings. It outlines the 14 DMTs currently available through the Australian Pharmaceutical Benefits Scheme and eight through the New Zealand Pharmaceutical Schedule, including the unique efficacy, safety and monitoring considerations of each. Through these guidelines, we aim to support safe, timely and effective management of patients with MS in Australia and New Zealand.