Медицинская библиотека · Reumatologia clinica · 2018

Noninfectious aortitis: Experience with tocilizumab in a regional hospital.

Aldasoro Cáceres Vicente, Ibáñez Bosch Rosario, Rivas Zavaleta Nathalí, Álvarez Rodríguez Belén, Intxausti Irazábal Juan José, Jiménez de Aberasturi Juan Ramón de Dios, Ruibal Escribano Ana, Maíz Alonso Olga, Calvo Alén Jaime

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Аннотация

OBJECTIVES

Describe patients with noninfectious aortitis and their response to treatment in a regional hospital.

METHODS

Review of patients with noninfectious aortitis, diagnostic technique used and immunosuppressive therapy received.

RESULTS

We report 8 patients (7 women and one man) diagnosed with aortitis by positron emission tomography (PET). The mean age was 69years (interquartile range [IQR] 62-72.2). Three months of treatment with tocilizumab improved symptoms, erythrocyte sedimentation rate and C-reactive protein level (P<.001 and P<.012, respectively) in the 6 patients in whom it was used.

CONCLUSIONS

Tocilizumab was an effective and safe treatment in those patients diagnosed with aortitis refractory to steroids and conventional immunosuppressive therapy.

Для цитирования: Aldasoro Cáceres Vicente, Ibáñez Bosch Rosario, Rivas Zavaleta Nathalí, Álvarez Rodríguez Belén, Intxausti Irazábal Juan José, Jiménez de Aberasturi Juan Ramón de Dios, Ruibal Escribano Ana, Maíz Alonso Olga, Calvo Alén Jaime. Noninfectious aortitis: Experience with tocilizumab in a regional hospital.. Reumatologia clinica. 2018. DOI: 10.1016/j.reuma.2017.12.014.

Предметные рубрики MeSH

Aged Antibodies, Monoclonal, Humanized Aortitis Female Hospitals Humans Male Middle Aged Retrospective Studies Spain

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