Emerging infectious diseases · 2023
Genomic Characteristics of Emerging Intraerythrocytic Anaplasma capra and High Prevalence in Goats, China.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Lin Zhe-Tao, Du Li-Feng, Zhang Ming-Zhu, Han Xiao-Yu, Wang Bai-Hui, Meng Jiao, Yu Fu-Xun, Zhou Xiao-Quan, Wang Ning, Li Cheng, Wang Xiao-Yang, Liu Jing, Gao Wan-Ying, Ye Run-Ze, Xia Luo-Yuan, Sun Yi, Jia Na, Jiang Jia-Fu, Zhao Lin, Cui Xiao-Ming, Zhan Lin, Cao Wu-Chun
Аннотация
Anaplasma capra is an emerging tickborne human pathogen initially recognized in China in 2015; it has been reported in ticks and in a wide range of domestic and wild animals worldwide. We describe whole-genome sequences of 2 A. capra strains from metagenomic sequencing of purified erythrocytes from infected goats in China. The genome of A. capra was the smallest among members of the genus Anaplasma. The genomes of the 2 A. capra strains contained comparable G+C content and numbers of pseudogenes with intraerythrocytic Anaplasma species. The 2 A. capra strains had 54 unique genes. The prevalence of A. capra was high among goats in the 2 endemic areas. Phylogenetic analyses revealed that the A. capra strains detected in this study were basically classified into 2 subclusters with those previously detected in Asia. Our findings clarify details of the genomic characteristics of A. capra and shed light on its genetic diversity.