Periprosthetic Infections: Five Steps to Keep Moving Forward in 2021.

The 2010 to 2020 decade produced remarkable advances in the understanding of periprosthetic joint infections (PJI). However, the challenges that surgeons and clinical researchers will face in the coming decade are many. Among the tactics that should comprise the strategy to keep moving forward are: (1) The incorporation of value-based healthcare concepts in PJI diagnosis. (2) Personalized approaches to estimate PJI risk and prevent it. (3) The concentration of PJI cases in multidisciplinary superspecialized units of treatment. (4) The use of a uniform definition to categorize failed and successful episodes of treatment. (5) Using the best available evidence as a benchmark to guide daily bedside decision-making.