Neurological research · 2026
Somatosensory evoked potentials in neuromyelitis optica spectrum disorders.
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Hernandez Fustes Otto Jesus, Kay Cláudia Suemi Kamoi, Lorenzoni Paulo José, Ducci Renata Dal-Pra, Werneck Lineu Cesar, Scola Rosana Herminia
Аннотация
INTRODUCTION: Neuromyelitis optica spectrum disorders (NMOSD) are rare antibody-mediated disorders of the central nervous system with a predilection for the spinal cord and optic nerves.
OBJECTIVE: Our objective is to evaluate the dorsolemniscal system using the somatosensory evoked potential, specifically the registration of the N20 and P40 waves.
METHODS: The Somatosensory evoked potentials (SSEP) were prospectively performed in 13 patients with NMOSD. All the patients were recruited from the outpatient clinic of a demyelinating diseases center from Southern Brazil.
RESULTS: We evaluated 12 female with mean age of 42 years-old and one man of 25 years-old. When categorized in relation to the variable SSEP (Normal vs. Abnormal), there was a statistical difference in relation to N20, N21 and P40 latencies.
CONCLUSION: SSEP showed a significant increase in N20 and P40 latencies. SSEP is a non-invasive, painless, fast and low-cost exam which provides neurophysiological data for diagnosis of NMOSD.
OBJECTIVE: Our objective is to evaluate the dorsolemniscal system using the somatosensory evoked potential, specifically the registration of the N20 and P40 waves.
METHODS: The Somatosensory evoked potentials (SSEP) were prospectively performed in 13 patients with NMOSD. All the patients were recruited from the outpatient clinic of a demyelinating diseases center from Southern Brazil.
RESULTS: We evaluated 12 female with mean age of 42 years-old and one man of 25 years-old. When categorized in relation to the variable SSEP (Normal vs. Abnormal), there was a statistical difference in relation to N20, N21 and P40 latencies.
CONCLUSION: SSEP showed a significant increase in N20 and P40 latencies. SSEP is a non-invasive, painless, fast and low-cost exam which provides neurophysiological data for diagnosis of NMOSD.