Journal of neurosurgery. Case lessons · 2025
Simple rigid skull base reconstruction with resorbable unsintered hydroxyapatite/poly-l-lactide plate in endoscopic endonasal skull base tumor surgery: illustrative case.
СтатьяНазвание и аннотация: Перевод в очереди
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Manthawornsiri Kittipit, Morisako Hiroki, Nagahama Atsufumi, Ikegami Masaki, Hazunga Rayford, Liew Boon Seng, Goto Takeo
Аннотация
BACKGROUND: Skull base reconstruction following an extended endoscopic endonasal approach (EEA) is essential for preventing postoperative CSF leakage. Despite recent advancements in surgical techniques and materials, CSF leakage remains a significant complication. This report presents a rigid reconstruction technique utilizing a resorbable unsintered hydroxyapatite/poly-l-lactide (u-HA/PLLA) plate to reduce postoperative CSF leakage.
OBSERVATIONS: Between May 2024 and June 2025, this method was used in 10 cases of extended EEA involving high-flow intraoperative CSF leaks and bone defects more than 25 mm. Notably, no postoperative CSF leakage was observed following the introduction of the u-HA/PLLA plate.
LESSONS: This material offers a unique combination of flexibility and mechanical strength comparable to cortical bone, along with osteoconductivity and bioresorbability, while producing negligible interference on postoperative imaging. These properties make it a highly promising material for skull base reconstruction. https://thejns.org/doi/10.3171/CASE25544.
OBSERVATIONS: Between May 2024 and June 2025, this method was used in 10 cases of extended EEA involving high-flow intraoperative CSF leaks and bone defects more than 25 mm. Notably, no postoperative CSF leakage was observed following the introduction of the u-HA/PLLA plate.
LESSONS: This material offers a unique combination of flexibility and mechanical strength comparable to cortical bone, along with osteoconductivity and bioresorbability, while producing negligible interference on postoperative imaging. These properties make it a highly promising material for skull base reconstruction. https://thejns.org/doi/10.3171/CASE25544.