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Войти в исследования Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020
Septic Arthritis in Immunosuppressed Patients: Do Laboratory Values Help?
СтатьяНазвание и аннотация: Перевод в очереди
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Bell Jared, Rasmussen Luke, Kumar Arun, Heckman Michael G, Lesser Elizabeth R, Whalen Joseph, Shi Glenn G, Wilke Benjamin K
Аннотация
UNLABELLED: Previous studies have recommended synovial fluid cell count thresholds of 50,000 cells/mm-3 to diagnose septic arthritis; however, data to support this are limited. It is also unknown if this value is valid in immunosuppressed patients.
METHODS: We retrospectively reviewed 33 immunosuppressed patients treated at our institution from 2008 to 2018. We compared culture-positive patients with culture-negative patients.
RESULTS: We found no statistically significant differences in synovial fluid cell count, percent synovial fluid neutrophils, erythrocyte sedimentation rate, or C-reactive protein between the groups (all P = 0.081). The median synovial fluid cell count in the culture-positive cohort was 29,000 cells/mm-3, with only 31.2% having >50,000 cells/mm-3.
CONCLUSION: Traditional synovial fluid cell thresholds are not a reliable method of diagnosing septic arthritis in immunosuppressed patients.
METHODS: We retrospectively reviewed 33 immunosuppressed patients treated at our institution from 2008 to 2018. We compared culture-positive patients with culture-negative patients.
RESULTS: We found no statistically significant differences in synovial fluid cell count, percent synovial fluid neutrophils, erythrocyte sedimentation rate, or C-reactive protein between the groups (all P = 0.081). The median synovial fluid cell count in the culture-positive cohort was 29,000 cells/mm-3, with only 31.2% having >50,000 cells/mm-3.
CONCLUSION: Traditional synovial fluid cell thresholds are not a reliable method of diagnosing septic arthritis in immunosuppressed patients.