Self-Reported Neurological Symptoms Two Years After Hospital Discharge Among COVID-19 Survivors.

BACKGROUND

The acute stage of COVID-19 often presents with neurological manifestations.

OBJECTIVE

This study aims to investigate the long-term neurological effects on survivors.

METHODS

This study recruited 1,546 COVID-19 survivors from Wuhan, including 1,119 nonsevere cases and 427 severe survivors. Participants were interviewed two years after discharge to report their neurological symptoms. The neurological symptoms of COVID-19 were compared between survivors of severe and nonsevere COVID-19.

RESULTS

Among the 1,546 COVID-19 survivors, 44.24% discovered at least one neurological symptom. The most prevalent self-reported symptom was fatigue (28.33%), memory deficit (13.26%), attention deficit (9.96%), myalgia (8.34%), dizziness (3.82%), and headache (2.52%). Severe cases had higher incidences of fatigue, myalgia, memory deficit, attention deficit than nonsevere cases. Older age, severe COVID-19, and comorbidity burden were associated with long-term neurological symptoms.

CONCLUSION

Neurological symptoms are common among COVID-19 survivors, especially in severe cases.