Cureus · 2025
Potential of a Novel Patient-Reported Outcome Assessment Method Utilizing Illustrations in Rheumatoid Arthritis.
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Koyama Kensuke, Koizumi Ryousuke
Аннотация
OBJECTIVES: We investigated whether the "Okomarigoto sheet," a novel patient-reported outcome measure that utilizes illustrations, correlates with disease activity and the Health Assessment Questionnaire Disability Index (HAQ-DI) in rheumatoid arthritis.
METHODS: The Okomarigoto sheet comprises five items each for morning stiffness, pain, and fatigue. Individual items are scored as follows: severe symptoms = 2, mild symptoms = 1, no symptoms = 0. The total score ranges from 0 to 30; higher scores indicate greater symptom burden. Correlations between Okomarigoto sheet scores, disease activity scores, and the HAQ-DI were analyzed in 332 patients. Scores were compared between patients in remission (HAQ-DI ≤ 0.5) and not in remission.
RESULTS: Correlations between the total Okomarigoto sheet score and Disease Activity Score using 28-joint count C-reactive protein, Clinical Disease Activity Index, and Simplified Disease Activity Index were 0.488, 0.591, and 0.572, respectively. The correlation between the total Okomarigoto sheet score and HAQ-DI was 0.593. The mean Okomarigoto sheet score was significantly lower in patients achieving HAQ-DI remission compared to those not in remission (2.47 vs. 10.4, respectively; p < 0.01).
CONCLUSIONS: This novel patient-reported outcome measure performed comparably to existing measures, correlating strongly with disease activity and disability.
METHODS: The Okomarigoto sheet comprises five items each for morning stiffness, pain, and fatigue. Individual items are scored as follows: severe symptoms = 2, mild symptoms = 1, no symptoms = 0. The total score ranges from 0 to 30; higher scores indicate greater symptom burden. Correlations between Okomarigoto sheet scores, disease activity scores, and the HAQ-DI were analyzed in 332 patients. Scores were compared between patients in remission (HAQ-DI ≤ 0.5) and not in remission.
RESULTS: Correlations between the total Okomarigoto sheet score and Disease Activity Score using 28-joint count C-reactive protein, Clinical Disease Activity Index, and Simplified Disease Activity Index were 0.488, 0.591, and 0.572, respectively. The correlation between the total Okomarigoto sheet score and HAQ-DI was 0.593. The mean Okomarigoto sheet score was significantly lower in patients achieving HAQ-DI remission compared to those not in remission (2.47 vs. 10.4, respectively; p < 0.01).
CONCLUSIONS: This novel patient-reported outcome measure performed comparably to existing measures, correlating strongly with disease activity and disability.