Peptoniphilus asaccharolyticus-associated septic arthritis and osteomyelitis in a woman with osteoarthritis and diabetes mellitus.

Peptoniphilus asaccharolyticus, a Gram-positive obligatory anaerobic coccus, is a commensal of the human vagina and gut and can be an opportunistic pathogen in immunocompromised patients. It is usually part of polymicrobial anaerobic infections such as skin and soft tissue infections in diabetics, bone and joint infections and surgical site infections; however, infections caused by P. asaccharolyticus in pure culture have been reported as well. Herein, we describe a case of septic arthritis and osteomyelitis caused by P. asaccharolyticus in a woman with osteoarthritis and diabetes mellitus.