[Cytochemical study of leukocyte cationic proteins in rheumatoid arthritis patients].

The markers of granulocyte order non-ferment cation proteins (CP) have pronounced bactericide, vascular-permeable and anticoagulant effect. In connection with the participation of leukocyte ferment and non-ferment systems in the formation of immune inflammations, the cytochemical studies on CP in neutrophil polymorphonuclears in rheumatoid arthritis (RA) are of certain importance. A cytochemical method in confirming CP was applied upon smears of peripheral blood of 54 patients with RA and 90 healthy subjects. The results were presented in a mean cytochemical coefficient according to Astaldi and Verga. A significant reduction of CP was established in the leukocytes of patients with RA regardless of the form - sero-negative or sero-positive. Most likely, immune conditioned changes in leukocyte metabolism were present in both forms which no doubt had an effect on their participation in the protective reactions of organism.