[Comparison of biometric and structural ocular manifestations of Marfan syndrome in twins].

A pair of 16-year-old twin brothers presented to our hospital. The younger brother had been losing vision in his left eye for 6 months, and the older brother had been losing vision in both eyes for 6 months. Both patients were 2.05 meters tall and lean with spider-like fingers (toes). They had lens subluxation and a leopard-shaped fundus in both eyes. Their ocular manifestations, including anterior and posterior corneal curvature, total corneal refractive power, anterior and posterior and total corneal astigmatism, corneal thickness, and axial length, were relatively consistent. The twin brothers were both diagnosed with Marfan syndrome and bilateral lens subluxation, which is a relatively rare clinical condition. The younger brother underwent posterior scleral reinforcement for retinal foveoschisis in the left eye, and the retina was basically attached after surgery. The older brother was treated with optometry and frame glasses. (Chin J Ophthalmol, 2021, 57: 540-543).