Медицинская библиотека · American journal of ophthalmology · 2006

Orbital cellulitis in a patient receiving infliximab for Ankylosing spondylitis.

Roos Jonathan C P, Ostor Andrew J K

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Аннотация

PURPOSE: To describe a case of orbital cellulitis arising in a patient treated with an anti-TNFalpha agent.

DESIGN

Single interventional case report.

METHODS

A 42-year-old man developed severe unilateral orbital cellulitis while receiving infliximab (Remicade, Centocor) treatment for Ankylosing spondylitis (AS) as part of the open-label phase of a trial conducted at our tertiary referral center. Cultures grew Staphylococcus aureus.

RESULTS

Infliximab treatment was stopped and the patient made a full recovery after receiving appropriate antibiotic therapy. Infliximab therapy was resumed after three weeks.

CONCLUSIONS

Clinical vigilance is warranted when treating patients with anti-TNFalpha agents as these are associated with a diverse and growing number of ophthalmic complications. Resolved infection does not preclude the use of such agents.

Для цитирования: Roos Jonathan C P, Ostor Andrew J K. Orbital cellulitis in a patient receiving infliximab for Ankylosing spondylitis.. American journal of ophthalmology. 2006. DOI: 10.1016/j.ajo.2005.11.017.

Предметные рубрики MeSH

Adult Amoxicillin-Potassium Clavulanate Combination Anti-Bacterial Agents Antibodies, Monoclonal Cefotaxime Cellulitis Drug Therapy, Combination Eye Infections, Bacterial Humans Infliximab Male Microbial Sensitivity Tests Orbital Diseases Randomized Controlled Trials as Topic Spondylitis, Ankylosing Staphylococcal Infections Staphylococcus aureus Tumor Necrosis Factor-alpha

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