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DOI 10.1182/hematology.2024000575

Медицинская библиотека · Hematology. American Society of Hematology. Education Program · 2024

When to use stem cell transplantation for classical Hodgkin lymphoma.

Kc Rebika, Shrestha Rojeena Koju, Shrestha Sweta, Shrestha Rohit, Bista Durga

СтатьяОбзорПоддержка NIH: внешняя программаПеревод пока не подготовлен

Аннотация

PURPOSE: Chronic low back pain (cLBP) is a commonly occurring and debilitating disorder that impacts health related quality of life (HRQOL) which in turn affects their perception toward pain medication. This study was carried on to assess the association between HRQOL and pain medication perceptions among cLBP patients. The study aims to enhance patient-centered care by identifying sociodemographic traits, common therapeutic drugs, and associations between HRQOL and pain medication perceptions.

PATIENTS AND

METHODS

A cross-sectional study design was employed, involving 350 patients diagnosed with cLBP the Orthopedics and Traumatology Outpatient Department of Dhulikhel Hospital (DH), Nepal. Data collection was performed via two structured of questionnaires; WHO Quality of Life-BREF (WHOQOL-BREF) for assessing HRQOL and the Pain Medication Attitude Questionnaire (PMAQ -14) for evaluating patients' perception of pain medication.

RESULTS

The study revealed notable negative correlations between concerns over addiction, side-effects, tolerance, and withdrawal and both overall quality of life (OQOL) (rs = -0.273, rs = -0.160, rs = -0.287 and rs = -0.304) and physical health domain (PD) (rs = -0.265, rs = -0.108, rs = -0.307 and rs = -0.272). This suggests that greater concerns regarding these factors were linked to a lower quality of life (QoL). However, the perceived necessity for pain medication displayed a slight positive correlation with general health satisfaction (GHS) of QoL where (rs = 0.132), whereas concerns such as scrutiny with Social Relationship Domain (SRD) (rs = -0.105) and mistrust in doctor showed weaker and negligible associations.

CONCLUSION

This study revealed that transformed OQOL was moderate with physical and psychological domains being the most impaired. Among the four domain scores, the highest score was in the SRD, while PD scored the lowest. Participants have neither good nor bad perceptions of QoL and are dissatisfied with their health showing significant concerns about addiction, side effects, and withdrawal, while societal judgement was minimal.

Для цитирования: Kc Rebika, Shrestha Rojeena Koju, Shrestha Sweta, Shrestha Rohit, Bista Durga. When to use stem cell transplantation for classical Hodgkin lymphoma.. Hematology. American Society of Hematology. Education Program. 2024. DOI: 10.1182/hematology.2024000575.

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