Complications Associated with Intra-Articular and Extra-Articular Corticosteroid Injections.

Side effects of corticosteroids can occur in association with both intra-articular and extra-articular injections. Less-severe reactions include skin reactions and flare responses. Although rare, worrisome complications such as infections, tendon ruptures, and osteonecrosis can occur. It is important to note the effect of corticosteroids on blood glucose levels, particularly for patients with diabetes. Corticosteroid injections have visual side effects with a known relation to central serous chorioretinopathy.