Fa yi xue za zhi · 2007
[Postmortem changes of liver phosphofructokinase-2 level in rats following different causes of death].
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Jin Ju, Li Bin, Jiao Bai-Guang, Fu Jia, Huang Hong, Song Yu, Peng Qi-Yi, Liao Zhi-Gang
Аннотация
OBJECTIVE: To study the changes of liver phosphofructokinase-2 (PFK-2) level at different postmortem intervals as well as due to different causes of death.
METHODS: One hundred and five rats were randomly divided into 3 groups and the rats were sacrificed by either bleeding, suffocating, and neck breaking, respectively. The content of liver PFK-2 at 0, 1, 2, 4, 8, 12 and 24 hours following death were studied using immunohistochemishtry and image analysis.
RESULTS: PFK-2 content of the rat's liver in all 3 groups showed a linear decrease at different postmortem intervals with no significant statistical differences found between the different groups.
CONCLUSION: PFK-2 level in rat liver appears to decrease linearly in correlation with prolonged PMI.
METHODS: One hundred and five rats were randomly divided into 3 groups and the rats were sacrificed by either bleeding, suffocating, and neck breaking, respectively. The content of liver PFK-2 at 0, 1, 2, 4, 8, 12 and 24 hours following death were studied using immunohistochemishtry and image analysis.
RESULTS: PFK-2 content of the rat's liver in all 3 groups showed a linear decrease at different postmortem intervals with no significant statistical differences found between the different groups.
CONCLUSION: PFK-2 level in rat liver appears to decrease linearly in correlation with prolonged PMI.