Surgical neurology international · 2025
Solitary fibrous tumor of the spine.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Alajmi Norah Abdullah, Aldhafeeri Wafa Faisal, Alsadrani Nora Saleh, Abdullah Jamal Mohammed, Alghabban Fatmah Abdulrahim, Faqihi Jawaher Abdulrahman, Alqwa Ahmed Raniah Mohammed, Jabri Hussam Essam
Аннотация
BACKGROUND: Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that infrequently involve the central nervous system, particularly the spine. Spinal SFTs are typically intradural extramedullary lesions that mimic common tumors such as meningiomas or schwannomas. Our case highlights how an atypical spinal SFT was diagnosed on magnetic resonance (MR) and successfully resected.
CASE DESCRIPTION: A 55-year-old female with a history of chronic nocturnal low back pain and multiple falls presented with urinary incontinence alone. The spinal MR imaging (MRI) revealed an intradural, extramedullary, lobulated contrast-enhancing lesion at T7. The lesion was resected utilizing a hemi-laminectomy/tubular retractor. Postoperatively, the patient recovered normal function, and the MR confirmed gross total tumor excision. The histopathology confirmed a solitary fibrous tumor (central nervous system [CNS] World Health Organization grade 1), composed of spindle cells in a collagenous stroma with thin-walled, staghorn-like vessels. Immunohistochemistry showed focal vimentin positivity and negative STAT6 staining, supporting a lowgrade SFT diagnosis. Eighteen months later, the MRI showed enhancement at the surgical site but without a clear mass; an open biopsy confirmed normal inflammatory changes, but no tumor recurrence.
CONCLUSION: Spinal SFTs are exceedingly rare neoplasms that can mimic more common spinal tumors, and early diagnosis with surgical biopsy and immunohistochemical confirmation is essential to ensure accurate management.
CASE DESCRIPTION: A 55-year-old female with a history of chronic nocturnal low back pain and multiple falls presented with urinary incontinence alone. The spinal MR imaging (MRI) revealed an intradural, extramedullary, lobulated contrast-enhancing lesion at T7. The lesion was resected utilizing a hemi-laminectomy/tubular retractor. Postoperatively, the patient recovered normal function, and the MR confirmed gross total tumor excision. The histopathology confirmed a solitary fibrous tumor (central nervous system [CNS] World Health Organization grade 1), composed of spindle cells in a collagenous stroma with thin-walled, staghorn-like vessels. Immunohistochemistry showed focal vimentin positivity and negative STAT6 staining, supporting a lowgrade SFT diagnosis. Eighteen months later, the MRI showed enhancement at the surgical site but without a clear mass; an open biopsy confirmed normal inflammatory changes, but no tumor recurrence.
CONCLUSION: Spinal SFTs are exceedingly rare neoplasms that can mimic more common spinal tumors, and early diagnosis with surgical biopsy and immunohistochemical confirmation is essential to ensure accurate management.