Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
[On the results of a multicenter, open, observational, non-interventional study of the efficacy and safety of nimesulide (Nise) in combination with muscle relaxants in patients with acute back pain].
СтатьяМногоцентровое исследованиеНаблюдательное исследованиеАннотация на английскомНазвание и аннотация: Перевод в очереди
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Iakupov E Z, Barantcevich E R, Barulin A E, Kurushina O V, Gamieva R A, Zagidullina K L, Garafutdinova A R
Аннотация
OBJECTIVE: To study the efficacy and safety of using Nise and Tolperisone in the treatment of patients with acute low back pain (ALBP).
MATERIAL AND METHODS: An open observational non-interventional study of the efficacy and safety of Nise (1 tablet of 100 mg in the morning and evening) in combination with the muscle relaxant Tolperisone for 14 days was conducted in patients with acute LBP. The efficacy and safety of using Nise and Tolperisone in patients with acute low back pain was analyzed using a visual analogue pain scale (VAS), the Roland-Morris questionnaire, SPID, the clinical global impression (CGI), and a study of patient diary data.
RESULTS: A decrease in pain severity was noted according to the VAS scale, signs of an improvement in functional status were revealed according to the Roland-Morris questionnaire, and high treatment efficacy was revealed according to the patient and doctor according to the CGI questionnaire.
CONCLUSION: The use of Nise and Tolperisone in patients with LBP is effective and safe.
MATERIAL AND METHODS: An open observational non-interventional study of the efficacy and safety of Nise (1 tablet of 100 mg in the morning and evening) in combination with the muscle relaxant Tolperisone for 14 days was conducted in patients with acute LBP. The efficacy and safety of using Nise and Tolperisone in patients with acute low back pain was analyzed using a visual analogue pain scale (VAS), the Roland-Morris questionnaire, SPID, the clinical global impression (CGI), and a study of patient diary data.
RESULTS: A decrease in pain severity was noted according to the VAS scale, signs of an improvement in functional status were revealed according to the Roland-Morris questionnaire, and high treatment efficacy was revealed according to the patient and doctor according to the CGI questionnaire.
CONCLUSION: The use of Nise and Tolperisone in patients with LBP is effective and safe.