[Treatment of steroid-dependent minimal change-nephrotic syndrome with mycophenolate mofetil].

Here we report two male patients, 16 and 20 years-old respectively, with minimal-change nephrotic syndrome showing frequent relapses and steroid dependence. Treatment with cyclosporin did not prevent the appearance of new relapses and both patients developed cyclosporin-dependence. The introduction of mycophenolate mofetil (500-15,000 mg/day) was followed by a sustained complete remission in both cases, without secondary effects.