Histochemical investigation of the activity of oxidoreductases in the skin lesions of lepromatous leprosy patients.

THIS PAPER REPORTS AN INVESTIGATION OF THE ACTIVITY OF THREE BASIC GROUPS OF OXIDOREDUCTASES IN LEPROMATOUS LEPROSY: specific dehydrogenases, flavoprotein enzymes, and cytochrome oxidase. The activity of the enzymes was studied before treatment, at various stages of treatment during exacerbations, and in the stage of regression. The data obtained are of importance for evaluating metabolic process in the cells of the specific infiltrates and the dermal connective tissue in leprosy, for determining the nature and intensity of the inflammatory process, and for control purposes in cases of regression.