[Clinical practice guidelines for evaluation and treatment of osteoporosis associated to endocrine and nutritional conditions. Bone Metabolism Working Group of the Spanish Society of Endocrinology].
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Reyes García Rebeca, Jódar Gimeno Esteban, García Martín Antonia, Romero Muñoz Manuel, Gómez Sáez José Manuel, Luque Fernández Inés, Varsavsky Mariela, Guadalix Iglesias Sonsoles, Cano Rodriguez Isidoro, Ballesteros Pomar María Dolores, Vidal Casariego Alfonso, Rozas Moreno Pedro, Cortés Berdonces María, Fernández García Diego, Calleja Canelas Amparo, Palma Moya Mercedes, Martínez Díaz-Guerra Guillermo, Jimenez Moleón José J, Muñoz Torres Manuel, Grupo de Metabolismo Mineral de la Sociedad Espa˜nola de Endocrinología y Nutrición
Аннотация
PARTICIPANTS: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology, a methodologist, and a documentalist.
METHODS: Recommendations were formulated according to the GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) to describe both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed), using the following terms associated to the name of each condition: AND "osteoporosis", "fractures", "bone mineral density", and "treatment". Papers in English with publication date before 18 October 2011 were included. Current evidence for each disease was reviewed by two group members, and doubts related to the review process or development of recommendations were resolved by the methodologist. Finally, recommendations were discussed in a meeting of the Working Group.
CONCLUSIONS: The document provides evidence-based practical recommendations for evaluation and management of endocrine and nutritional diseases associated to low bone mass or an increased risk of fracture. For each disease, the associated risk of low bone mass and fragility fractures is given, recommendations for bone mass assessment are provided, and treatment options that have shown to be effective for increasing bone mass and/or to decreasing fragility fractures are listed.