Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2015
Extracorporeal photopheresis for the treatment of autoimmune diseases.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Adamski Jill, Kinard Theresa, Ipe Tina, Cooling Laura
Аннотация
The immune system is tasked with the unique challenge of recognizing foreign pathogens and damaged cells while at the same time preserving and protecting the integrity of "self". When this process fails, severe consequences including cancer and autoimmunity are the end result. Current therapies aimed at treating autoimmune disorders result in generalized immunosuppression and place the patient at increased risk for infection and malignancy. ECP is a potential therapeutic intervention that recapitulates natural physiologic processes of tolerance induction to restore immune homeostasis. Several clinical trials suggest that ECP may be used to treat a broad spectrum of autoimmune diseases.
Предметные рубрики MeSH
AnimalsApoptosisArthritis, RheumatoidAutoimmune DiseasesClinical Trials as TopicCrohn DiseaseDiabetes Mellitus, Type 1EosinophiliaEpidermolysis Bullosa AcquisitaFasciitisHomeostasisHumansImmune ToleranceImmunosuppression TherapyImmunosuppressive AgentsLichen PlanusLupus Erythematosus, SystemicMultiple SclerosisPemphigusPhotopheresisPsoriasisScleroderma, SystemicScleromyxedemaSpondylitis, AnkylosingT-Lymphocytes, Regulatory