Seizures as Presenting Complaint of Cerebral Cortex Involvement in Leprosy.

Leprosy, recognized as one of the ancient diseases, predominantly affects the integumentary system and peripheral nerves. Nevertheless, central nervous system (CNS) involvement is a rare occurrence, with cortical manifestations being exceedingly infrequent. We present a case that aligns with this rarity, showcasing diffuse hyperintensities on magnetic resonance imaging (MRI) within the cortical region of the brain. The patient's clinical presentation was marked by seizures, necessitating targeted therapeutic interventions.