The Journal of the Association of Physicians of India · 2026
Treatment of Tuberculosis in Renal Insufficiency.
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Gupta Nikhil, Rani Harshita, Kacker Rishabh, Prasad Rajendra, Deshmukh Rishikesh Balasaheb
Аннотация
Tuberculosis (TB) is a significant global health challenge, particularly in patients with renal insufficiency, where both the disease and its treatment are complicated by altered pharmacokinetics, immunosuppression, and increased risk of drug toxicity. Management of TB in patients with renal insufficiency is complex and necessitates an individualized, multidisciplinary approach. Careful dose adjustments, regimen selection, management of comorbid conditions, regular monitoring, and adherence to current guidelines can optimize outcomes while minimizing adverse effects. This article reviews current strategies and evidence-based approaches for the treatment of TB in patients with renal insufficiency, with a focus on drug selection, dose adjustment, and monitoring for toxicity and efficacy.