Osteomyelitis concurrently caused by Staphylococcus aureus and Mycobacterium tuberculosis.

We report the case of a 59-year-old woman who presented with fever and a cutaneous ulcer on her left ankle. In addition to Staphylococcus aureus growth from a blood culture, S aureus and Mycobacterium tuberculosis were both isolated from tissue specimens. This case highlights that osteomyelitis may be concurrently caused by S aureus and M tuberculosis. In a patient whose osteomyelitis due to S aureus responds poorly to clinical therapy, clinicians should suspect coexisting tuberculosis, especially in areas where tuberculosis is endemic.